Calling Dentists for New Research Study

Peri-implantitis is a top cause of implant failure and is even more complex to treat than periodontitis. 70% of Americans have periodontal disease, doubling risks for heart disease, diabetes, pre-term birth, even cancer. And periodontal disease is the primary cause of tooth loss with patients over 40 years old.

The National Institute of Health states, “The incidence of peri-implantitis was 28.6% in patients with a history of periodontitis, and 5.8% in those patients without a history of the disease”

Yet Mayo Clinic finds Chlorhexidine, the gold standard of periodontal rinses, also increases heart disease risk.

Is Peri-Implantitis a ticking time bomb for the 500,000 patients who have at least one implant?

Join us to prove efficacy of a new dental implant pre-op protocol to protect your patients.  Time is running out!

Measuring Efficacy of Periodontal Therapies in reducing Peri-Implantitis Risks: A Scientific Approach Research Protocols



Peri-implantitis is a top cause of implant failure and is even more complex to treat than periodontitis
Incidence of peri-implantitis is 28.6% in patients with periodontal disease history vs 5.8% without history of gum disease.1 500,000 patients could be facing peri-implantitis 10+ years post surgery.
70% of Americans have periodontal disease doubling risk for heart disease, diabetes, pre-term birth, cancer even Alzeimers’.
Periodontal disease is the primary cause of tooth loss in patients over 40 years old.
Chlorhexidine increases heart disease risks within 1 day of using twice.2


Many studies show the efficacy of one therapy or homecare product but periodontitis and peri-implantitis are multi-causal.
This study measures efficacy of a combination of perio therapies used in a defined protocol and includes:
Demographics, Health history, Family Health History, Bacteria Diagnosis
Scaling and Root Planing
Clean Kiss Organic Swish Mouthwash, Scrub toothpaste, Spray breath refresher, Support Anti-Inflammatory and Bone Nutraceuticals.
Laser Assisted Periodontal Therapy
30 Second Smile Scrub Brush
Hydrofloss oral irrigator

The study will also determine how well organic botanical home care compares to control groups.

PROTOCOL Appointment 1

Document Health History, Family Health History.
Diagnostics include:
Blood Pressure
Document Full Mouth Probe Scores
If 6 or more probe scores measure >3mm, is 40+ years old offer research enrollment whether or not seeking implants or on medication
Patient signs compliance and genetic consent agreement
Complete finger stick for A1c/Crp and Salivary Oral DNA Alert 2 Gene and My Perio Path tests
Start Patient on Clean Kiss 3 month Complete Kit.
3. Show patient Clean Kiss Use video
4. Appoint Laser/SRP ASAP
Place Oral DNA order and place sample in oral DNA mailer. Schedule weekly pickup.
Document Chairside notes in Oral DNA Portal. Schedule one hour appt in ASAP.

PROTOCOL Appointment 2

Use Laser to decontaminate entire mouth
Complete 2 quadrants SRP
Calculate 1 laser tx per mm pocket depth reduction desired
Complete full mouth LAPT as first laser tx.
Re-enforce complete homecare instructions
Appoint 1 hour in 2 weeks
Document in Oral DNA Clinical Notes Portal

PROTOCOL Appointment 3

Use Laser to decontaminate entire mouth
If needed complete remaining 2 quadrants SRP
Complete second LAPT TX
Re-enforce complete homecare instructions
Appoint Implant placement surgery in 2 weeks
Document in Oral DNA Clinical Notes Portal

PROTOCOL Appointment 4

Use Laser to decontaminate entire mouth
Place implant fixture
Re-enforce homecare use to promote healing
Appoint Surgical follow up in 2 weeks
Document Patient Notes in Oral DNA Clinical Notes Portal

PROTOCOL Appointment 5

Complete Post Op healing check
3rd Laser Round, if needed*
Otherwise, complete and document Full Mouth Probe
Complete second A1c/Crp test
Complete second My Perio Path Oral DNA test
To complete healing regimen set up homecare autoship to patient or supply 3 month complete kit
Appoint Implant tooth restoration in 3-6 months
Document Patient Notes
* If 3rd laser round is needed, call back in 2 weeks to complete protocol


For patient to be included in research results oral DNA forms must be completed and entered into clinical notes portal including the following:
1. % of Bleeding on Probing is calculated by #bleeding sites/#teethx6.
2. Bone loss–Mild, Medium, Severe
3. % of Probing scores >3 is calculated by #probe scores >3mm/#teethX6.
4. % of Bleeding on Probing is calculated by #bleeding sites/#teethx6.
5. Before and after A1c and Crp Scores
6, Document if High Blood Pressure.
7. Medications= Yes or No.
8. Tooth Loss= Yes or No.
9. Oral DNA Genetic Susceptibility test
10. Before and After My Perio Path Tests
11. Document # of ounces CK Swish used
12. Document # of both supplements taken


  1. Participants names will be listed on white paper results
  2. Oral DNA Labs will market research results (and participants) nationally
  3. Results will be presented at the American Academy of Implant Dentist meeting
  4. HCP Wellnet will publish results on social media
  5. Participants will have access to media for their PR and Marketing
  6. 1 syndicated Press Release announcing your joining the study
  7. Team protocol training ($1,500 value)


A minimum of 10 patients are required to participate.  You will need the following products to participate in the research:

Research Products for 10 patients include:

10 Alert 2 Periodontist Susceptibility and My Perio Pathogen tests (before therapy documentation)

10 My Perio Pathogen tests (documents after therapy)

20 A1c/Crp test (documents before and after therapy)

10 30 Second Smile Scrub Brush

10 Hydrofloss Oral Irrigators

10 3 month Clean Kiss Complete Kits (Each kit includes 3 32 oz bottles Swish mouthwash; 2 tubes Scrub toothpaste; 3 Spray breath refresher; 3 bottles ea Support Bone and Support Anti-Inflammatory)

No shipping



What is peri-implantitis (PI)? The prefix “peri” indicates the condition of being all around; “implant” relates, in this context, to a dental implant constructed of a porcelain crown with a titanium root; and the suffix “itis” indicates disease or inflammation. So, peri-implantitis is a state of disease or inflammation around a dental implant. The disease causes progressive bone loss, which is the determining factor for peri-implant disease.


What causes peri-implant disease? At the onset of this disease, there exists an imbalance between bacterial load (density of bacteria) and the host (the tissues surrounding the implant) defense.

Did you know that microbial species colonize an implant’s surface within the first 30 minutes after the implant? Then, between the 1st and the 12th weeks, bacterial load grows and then continues growing subsequently, especially in some species of bacteria. Bleeding on probing (BOP) and increase of probing depth (PD) over time are good indicators of loss of tissue supporting the implant. If bone loss, due to BOP and PD results, seems to be indicated, radiographs should be administered, first as a diagnostic and then as a monitoring strategy.


What are the risk indicators for peri-implant disease?

  • Placement in males
  • Placement in patients with a history of periodontitis – A 10-year longitudinal study showed PI incidence was 28.6% in those with a history of periodontitis; whereas, those without had 5.8%.
  • Crowded teeth associated with accumulation of plaque or pre-existing inflammation
  • Cement remnants for mechanical or biological complications

Smoking, long thought to be a risk factor, has not yet been clearly established as such because current study results are mixed, so further studies are needed to conclude one way or the other.


What can you do to prevent peri-implant disease?

Bone loss with dental implants results in the loss of implants. Key to survival of implants is daily oral hygiene and supportive periodontal therapy. A longitudinal 10-year study found patients with inconsistent attendance to a supportive maintenance program fared negatively regarding number of teeth lost and results for peri-implantitis (PI), bleeding on probing (BOP), and probing depth (PD).

Help us prove efficacy of a new pre-operative protocol.  Dentists: See if you qualify for participation.  Physicians: Contact us to see how you can support this research project.  Patients: Refer your dentist to us.  Together we can make HEALTH Contagious!

Questions? Contact Leona Meditz for 30% discount on participation products and  supplies 480-400-7358